Hydroxychloroquine, primarily known for its antimalarial properties, also exhibits immunomodulatory effects that can influence immune function. One of its key mechanisms involves altering the activity of immune cells, particularly T lymphocytes. Hydroxychloroquine interferes with the acidification of lysosomes within these cells, impairing their function. Lysosomes play crucial roles in various cellular processes, including antigen processing and presentation, as well as the regulation of inflammatory responses. By inhibiting lysosomal activity, hydroxychloroquine can modulate the activation and proliferation of T cells, thereby dampening certain aspects of the immune response.

Moreover, Hydroxychloroquine 400mg may also impact the production and release of pro-inflammatory cytokines, which are signaling molecules involved in orchestrating immune responses. By reducing the secretion of cytokines such as tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6), hydroxychloroquine can mitigate excessive inflammation associated with autoimmune conditions like rheumatoid arthritis and lupus erythematosus. However, the precise mechanisms underlying hydroxychloroquine's immunomodulatory effects are complex and not yet fully elucidated. Furthermore, while these properties contribute to its therapeutic efficacy in certain autoimmune diseases, they have also sparked interest in exploring hydroxychloroquine's potential role in managing inflammatory responses in other conditions, such as viral infections, although its effectiveness in this context remains subject to ongoing research and debate.